Pediatric Myocardial Stunning Underscores the Cardiac Toxicity of Conventional Hemodialysis Treatments
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چکیده
منابع مشابه
Myocardial Stunning with Hemodialysis: Clinical Challenges of the Cardiorenal Patient.
We discuss the current state of knowledge related to the pathogenesis of myocardial stunning as well as the potential mechanisms responsible for the clinical presentation of myocardial stunning in hemodialysis patients. We suggest future research areas for this critical and clinically important condition in this high-risk patient population. In consideration of acute and chronic changes seconda...
متن کاملMechanism of myocardial "stunning".
Among the numerous mechanisms proposed for myocardial stunning, three appear to be more plausible: 1) generation of oxygen radicals, 2) calcium overload, and 3) excitation-contraction uncoupling. First, the evidence for a pathogenetic role of oxygen-derived free radicals in myocardial stunning is overwhelming. In the setting of a single 15-minute coronary occlusion, mitigation of stunning by an...
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This study was undertaken to elucidate whether cal-adrenoceptor activity is beneficial to contractile dysfunction during reperfusion after a brief period of ischemia (stunned myocardium) in 54 open-chest dogs. Contractile dysfunction assessed by fractional shortening (FS) was observed 3 hours after the onset of reperfusion following 15 minutes of complete occlusion of the left anterior descendi...
متن کاملMyocardial dysfunction after resuscitation from cardiac arrest: an example of global myocardial stunning.
OBJECTIVES This study investigated the effect of prolonged cardiac arrest and subsequent cardiopulmonary resuscitation on left ventricular systolic and diastolic function. BACKGROUND Cardiac arrest from ventricular fibrillation results in cessation of forward blood flow, including myocardial blood flow. During cardiopulmonary resuscitation, myocardial blood flow remains suboptimal. Once the h...
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Background and Objective: The present study aimed to assess the role of magnesium sulfate (MgSO4) sup-plementation after cardiac surgery in pediatric patients, evaluating the incidence of cardiac complications, such as arrhythmia. Methods: In this study, 105 children scheduled for elective cardiac surgery were randomly divided into 3 groups. The first group, as the placebo group, received sali...
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ژورنال
عنوان ژورنال: Clinical Journal of the American Society of Nephrology
سال: 2009
ISSN: 1555-9041,1555-905X
DOI: 10.2215/cjn.05921108